| Passing | Rushing | Receiving | Ret | Misc | Fum | Fantasy | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Player | Opp | Yds | TD | Int | Yds | TD | Rec | Yds | TD | TD | FumTD | 2PT | Lost | Points |
Saquon Barkley RB - NYG | JAX | - | - | - | 1307 | 11 | 91 | 721 | 4 | - | - | 1 | - | 385.80 |
Christian McCaffrey RB - CAR View News | DAL | 50 | 1 | - | 1098 | 7 | 107 | 867 | 6 | - | - | - | 1 | 385.50 |
| @OAK | - | - | - | 1251 | 17 | 59 | 580 | 4 | - | - | 3 | 1 | 372.10 | |
| TB | - | - | - | 883 | 14 | 81 | 709 | 4 | - | - | 3 | - | 354.20 | |
Ezekiel Elliott RB - DAL View Videos | @CAR | - | - | - | 1434 | 6 | 77 | 567 | 3 | - | - | - | 1 | 329.10 |
James Conner RB - PIT IA View News | @CLE | - | - | - | 973 | 12 | 55 | 497 | 1 | - | - | 2 | 2 | 280.00 |
| HOU | - | - | - | 425 | 5 | 87 | 751 | 7 | - | - | - | - | 276.60 | |
| KC | - | - | - | 885 | 10 | 50 | 490 | 4 | - | - | 2 | - | 275.50 | |
| WAS | - | - | - | 940 | 7 | 50 | 446 | 3 | - | - | 1 | 2 | 246.60 | |
| @IND | - | - | - | 1168 | 8 | 43 | 296 | 1 | - | - | - | - | 243.40 | |
Tarik Cohen RB - CHI View Videos | @GB | 1 | 1 | - | 444 | 3 | 71 | 725 | 5 | - | - | - | 3 | 233.94 |
| Bye | - | - | - | 824 | 7 | 26 | 378 | 7 | - | - | - | - | 230.20 | |
| SEA | - | - | - | 1037 | 9 | 35 | 241 | 1 | - | - | - | - | 222.80 | |
Kenyan Drake RB - ARI View News | TEN | - | - | - | 535 | 4 | 53 | 477 | 5 | - | - | - | 1 | 206.20 |
| @DEN | - | - | - | 1151 | 9 | 20 | 163 | - | - | - | - | 2 | 201.40 | |
| @MIA | 14 | - | - | 1059 | 12 | 15 | 99 | - | - | - | - | 1 | 201.36 | |
| PIT | - | - | - | 996 | 8 | 20 | 149 | 2 | - | - | - | - | 194.50 | |
Tevin Coleman RB - SF | @PHI | - | - | - | 800 | 4 | 32 | 276 | 5 | - | - | - | - | 193.60 |
| @ARI | - | - | - | 1042 | 7 | 20 | 208 | 1 | - | - | - | 2 | 189.00 | |
Jordan Howard RB - PHI Q | @GB | - | - | - | 935 | 9 | 20 | 145 | - | - | - | - | 1 | 180.00 |
| CIN | - | - | - | 908 | 9 | 17 | 103 | 1 | - | - | 2 | 2 | 178.10 | |
T.J. Yeldon RB - BUF IA View News | @NYG | - | - | - | 414 | 1 | 55 | 487 | 4 | - | - | - | 1 | 173.10 |
Lamar Miller RB - HOU IR | @NE | - | - | - | 973 | 5 | 25 | 163 | 1 | - | - | - | 1 | 172.60 |
| CHI | - | - | - | 728 | 8 | 26 | 206 | 1 | - | - | - | 1 | 171.40 | |
| KC | - | - | - | 554 | 3 | 39 | 404 | 3 | - | - | - | 1 | 168.80 | |