| Passing | Rushing | Receiving | Ret | Misc | Fum | Fantasy | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Player | Opp | Yds | TD | Int | Yds | TD | Rec | Yds | TD | TD | FumTD | 2PT | Lost | Points |
| IND | - | - | - | 1305 | 13 | 64 | 788 | 6 | - | - | - | 2 | 383.30 | |
| @GB | 3983 | 34 | 11 | 586 | 3 | - | - | - | - | - | 2 | 3 | 347.92 | |
| @CLE | - | - | - | 1291 | 9 | 85 | 655 | 2 | - | - | - | 2 | 341.60 | |
| @MIN | - | - | - | 728 | 8 | 81 | 826 | 5 | 1 | - | 1 | 1 | 320.40 | |
| @CLE | - | - | - | - | - | 101 | 1533 | 9 | - | - | 1 | - | 310.30 | |
| JAX | - | - | - | - | - | 96 | 1378 | 13 | - | - | - | 1 | 309.80 | |
Cam Newton QB - CAR IA View News | @SF | 3302 | 22 | 16 | 754 | 6 | - | - | - | - | - | 1 | 1 | 299.48 |
| KC | 4577 | 32 | 8 | 28 | - | - | - | - | - | - | 2 | 3 | 295.88 | |
Kareem Hunt RB - CLE SUS | @NE | - | - | - | 1327 | 8 | 53 | 455 | 3 | - | - | - | 1 | 295.20 |
Alex Smith QB - WAS PUP | @NE | 4042 | 26 | 5 | 355 | 1 | - | - | - | - | - | - | 1 | 295.18 |
Melvin Gordon RB - LAC NWT | @DEN | - | - | - | 1105 | 8 | 58 | 476 | 4 | - | - | - | - | 288.10 |
| @DEN | - | - | - | 9 | - | 102 | 1393 | 6 | - | 1 | - | - | 284.20 | |
| @WAS | 3296 | 33 | 7 | 299 | - | - | - | - | - | - | 4 | 3 | 281.74 | |
| @MIN | - | - | - | 1124 | 12 | 58 | 416 | - | - | - | - | 3 | 278.00 | |
| PHI | 4093 | 27 | 13 | 179 | 4 | - | - | - | - | - | - | 5 | 277.62 | |
| ARI | 4446 | 29 | 10 | 98 | - | - | - | - | - | - | 2 | 7 | 273.64 | |
| @DEN | 4515 | 28 | 10 | -2 | - | - | - | - | - | - | - | 1 | 270.40 | |
| NYJ | - | - | - | 1138 | 6 | 59 | 448 | 2 | - | - | - | 1 | 263.60 | |
Drew Brees QB - NO IA View News | @MIN | 4334 | 23 | 8 | 12 | 2 | - | - | - | - | - | - | - | 262.56 |
| @DET | 21 | - | - | - | - | 109 | 1156 | 6 | - | - | 1 | 1 | 261.44 | |
Ben Roethlisberger QB - PIT IR View News | @CLE | 4251 | 28 | 14 | 47 | - | - | - | - | - | - | 2 | 1 | 260.74 |
| NYG | 3324 | 22 | 13 | 357 | 6 | - | - | - | - | - | - | 3 | 260.66 | |
Jarvis Landry WR - CLE View Videos | Bye | - | - | - | -7 | - | 112 | 987 | 9 | - | - | - | 2 | 260.00 |
| @MIN | - | - | - | - | - | 104 | 1245 | 5 | - | - | - | - | 258.50 | |
Jared Goff QB - LA View Videos | IND | 3804 | 28 | 7 | 51 | 1 | - | - | - | - | - | - | 3 | 255.26 |